Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Lock and Key Vs. Induced Fit Models

Biochemistry

6. Enzymes and Enzyme Kinetics

Lock and Key Vs. Induced Fit Models

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Multiple Choice

Select the best option that fills in the blanks appropriately in the order of their appearance.

The left graph depicts an energy diagram for the '_______' model of enzyme-substrate specificity, whereas the right diagram depicts an energy diagram for the modern '_' model. In the lock & key model, the enzyme binds tightly and precisely to the '_.' In the induced fit model, the enzyme binds weakly to the '_' and then changes conformation to bind tightly to the '_______.'

Lock & Key ; Induced fit ; transition state ; substrate ; product.

Lock & Key ; Induced fit ; substrate, transition state ; product.

Lock & Key ; Induced fit ; substrate; substrate; transition state.

Induced fit ; Lock & Key ; transition state; product; substrate.

Induced fit ; Lock & Key ; product; transition state; substrate.

Induced fit ; Lock & Key ; substrate ; product; transition state.

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Verified step by step guidance

Identify the two models of enzyme-substrate specificity: the 'Lock & Key' model and the 'Induced Fit' model.

Examine the left graph: it shows a single peak in the energy diagram, which is characteristic of the 'Lock & Key' model where the enzyme binds tightly and precisely to the substrate.

Examine the right graph: it shows a more complex energy diagram with an initial binding followed by a conformational change, characteristic of the 'Induced Fit' model where the enzyme initially binds weakly to the substrate and then changes conformation to bind tightly to the transition state.

Understand that in the 'Lock & Key' model, the enzyme-substrate complex (ES) is formed with a precise fit, while in the 'Induced Fit' model, the enzyme undergoes a conformational change to better fit the substrate and stabilize the transition state.

Select the correct answer based on the analysis: 'Lock & Key ; Induced fit ; substrate; substrate; transition state.'