Multiple Choice
Which of the following statements is false with respect to an enzyme's ability to catalyze a reaction?
6. Enzymes and Enzyme Kinetics
Activation Energy
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Which of the following is not a way that enzymes increase rates of reactions?
A
Binding of substrates in close proximity.
B
Covalently binding to the substrate.
C
Stabilization of the transition state.
D
Conformational changes in binding site slightly increases EA.
Verified step by step guidance1
Understand that enzymes are biological catalysts that increase the rate of reactions by lowering the activation energy (EA) required for the reaction to proceed.
Recognize that enzymes achieve this by various mechanisms, including binding substrates in close proximity, which increases the likelihood of reaction.
Note that enzymes can also stabilize the transition state, which is the high-energy state that reactants must reach for the reaction to occur, thereby lowering the activation energy.
Consider that some enzymes form temporary covalent bonds with substrates, which can help in stabilizing the transition state or in the conversion of substrates to products.
Realize that while conformational changes in the enzyme's binding site can occur, they typically facilitate substrate binding and catalysis rather than directly increasing the activation energy (EA). Thus, this is not a primary way enzymes increase reaction rates.
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