Draw the structure of the following amino acids, dipeptides, and tripeptides at low pH (pH 1) and high pH (pH 14). At each pH, assume that all functional groups that might do so are ionized.
d. Glu-Asp

Question

Draw the structure of the following amino acids, dipeptides, and tripeptides at low pH (pH 1) and high pH (pH 14). At each pH, assume that all functional groups that might do so are ionized.

d. Glu-Asp

Accepted Answer

Hello, everyone. Today, we have the following problem determine the structure of the given peptide at one high ph and two low ph assuming that all of its functional groups become ionized at each Ph level. So we have aspartic acid and we have alanine as our two amino acids that are essentially bonded together by a peptide bond. So if we draw the structure of our aspartic acid, we will get the following. And then if we draw a structure of alanine, you will get the following. Now note that each of these amino acids has a carboxylic acid group and an amino group. So to join these two into one DP time, they will be reacting and essentially the form that we have a carboxyl group of one amino acid forming a covalent bond with an amino group of the another amino acid. And we will lose water in the process. So we will lose water in this process. And so we will essentially get the following structure. So for our dipeptide, we'll first draw our aspartic acid as the N terminus and then we have our dipeptide bond and then we will draw our alanine as the C terminus. And so now we have our dipeptide. So we will first draw this at a, we will draw our two structures so that our first set of conditions can be high Ph. And the second set of conditions can be a low Ph. So if we have our first set of conditions at a high Ph, this means that we will have less protons since there's an inverse relationship between PH and protons. And as such, we will actually have no protonation of our amino group. And the carboxylic acid groups will exist as carboxylate an ions. So we will essentially have the following as our remaining structure. Now, if we have our second set of conditions are low Ph, this means that we have a high amount of protons, meaning that our carboxylic acids will stay proton and our amino groups will become proton. And so that will be reflected as such. And so with that, we have solved the problem overall, I hope this helped. And until next time.

Draw the structure of the following amino acids, dipeptides, and tripeptides at low pH (pH 1) and high pH (pH 14). At each pH, assume that all functional groups that might do so are ionized.
d. Glu-Asp

Verified video answer for a similar problem:

Key Concepts

Amino Acid Structure

Ionization at Different pH Levels

Peptide Bond Formation

Draw the structure of the following amino acids, dipeptides, and tripeptides at low pH (pH 1) and high pH (pH 14). At each pH, assume that all functional groups that might do so are ionized.d. Glu-Asp

Verified video answer for a similar problem:

Key Concepts

Amino Acid Structure

Ionization at Different pH Levels

Peptide Bond Formation

Draw the structure of the following amino acids, dipeptides, and tripeptides at low pH (pH 1) and high pH (pH 14). At each pH, assume that all functional groups that might do so are ionized.
d. Glu-Asp