Textbook Question
Examine the α-helix in Figure 18.1 and determine how many backbone C and N atoms are included in the loop between an amide hydrogen atom and the carbonyl oxygen to which it is hydrogen bonded.
Ch.18 Amino Acids and Proteins
McMurry8th EditionFundamentals of GOBISBN: 9780134015187
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Table of contents
- Ch.1 Matter and Measurements27
- Ch.2 Atoms and the Periodic Table20
- Ch.3 Ionic Compounds8
- Ch.4 Molecular Compounds23
- Ch.5 Classification & Balancing of Chemical Reactions12
- Ch.6 Chemical Reactions: Mole and Mass Relationships28
- Ch.7 Chemical Reactions: Energy, Rate and Equilibrium64
- Ch.8 Gases, Liquids and Solids24
- Ch.9 Solutions52
- Ch.10 Acids and Bases25
- Ch.11 Nuclear Chemistry22
- Ch.12 Introduction to Organic Chemistry: Alkanes57
- Ch.13 Alkenes, Alkynes, and Aromatic Compounds47
- Ch.14 Some Compounds with Oxygen, Sulfur, or a Halogen50
- Ch.15 Aldehydes and Ketones45
- Ch.16 Amines42
- Ch.17 Carboxylic Acids and Their Derivatives57
- Ch.18 Amino Acids and Proteins82
- Ch.19 Enzymes and Vitamins63
- Ch.20 Carbohydrates44
- Ch.21 The Generation of Biochemical Energy65
- Ch.22 Carbohydrate Metabolism45
- Ch.23 Lipids42
- Ch.24 Lipid Metabolism33
- Ch.25 Protein and Amino Acid Metabolism24
- Ch.26 Nucleic Acids and Protein Synthesis45
Chapter 18, Problem 30a
For each of the conjugated proteins described, identify to which class of conjugated protein it belongs.
a. Cholesterol is attached to this protein in order to move through the blood system.
Verified step by step guidance1
Step 1: Understand the concept of conjugated proteins. Conjugated proteins are proteins that are combined with a non-protein component, called a prosthetic group. The type of prosthetic group determines the class of the conjugated protein.
Step 2: Identify the prosthetic group in the given problem. In this case, cholesterol is attached to the protein. Cholesterol is a lipid molecule.
Step 3: Recall the classification of conjugated proteins. Proteins are classified based on their prosthetic group. For example, lipoproteins have lipids as their prosthetic group, glycoproteins have carbohydrates, and metalloproteins have metal ions.
Step 4: Match the prosthetic group (cholesterol, a lipid) to the appropriate class of conjugated protein. Since cholesterol is a lipid, the protein belongs to the class of lipoproteins.
Step 5: Conclude that the protein described in the problem is a lipoprotein, as it has cholesterol (a lipid) attached to it to facilitate its movement through the blood system.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Conjugated Proteins
Conjugated proteins are proteins that are covalently bonded to a non-protein group, known as a prosthetic group. These groups can be carbohydrates, lipids, or metal ions, and they play a crucial role in the protein's function. Understanding the nature of these attachments is essential for classifying the protein and determining its biological role.
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Digestion of Proteins Concept 1
Lipoproteins
Lipoproteins are a class of conjugated proteins that consist of proteins and lipids, such as cholesterol. They are essential for transporting lipids through the bloodstream, as lipids are not soluble in water. The classification of lipoproteins is based on their density and composition, which influences their function in lipid metabolism and cardiovascular health.
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Cholesterol Transport
Cholesterol transport refers to the mechanisms by which cholesterol is moved through the bloodstream, primarily via lipoproteins. This process is vital for maintaining cellular function and membrane integrity. Understanding how cholesterol is conjugated to proteins helps in identifying the specific class of conjugated protein involved in its transport, such as low-density lipoproteins (LDL) or high-density lipoproteins (HDL).
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Related Practice
Textbook Question
Consult the β-sheet in Figure 18.2 and (a) name the bonding responsible for the sheet formation and (b) identify the specific atoms responsible for this bonding.
Textbook Question
Complete the following two sentences with either globular or fibrous:
a. Proteins with secondary structure composed primarily of alpha-helix are___________ proteins.
Textbook Question
For each of the conjugated proteins described, identify to which class of conjugated protein it belongs.
b. Ionized zinc is attached to this protein so the protein can function.
Textbook Question
For each of the conjugated proteins described, identify to which class of conjugated protein it belongs.
c. Phosphate groups are attached to this protein.
Textbook Question
Both α-keratin and tropocollagen have helical secondary structure. How do these molecules differ in (a) amino acid composition and (b) three-dimensional structure?