Multiple Choice
Tryptophan regulates the trp operon by doing what?
12. Gene Regulation in Prokaryotes
Tryptophan Operon and Attenuation
Back12. Gene Regulation in Prokaryotes
Tryptophan Operon and Attenuation
- Multiple Choice
Attenuation uses what molecule to regulate the trp operon?
- Multiple Choice
What is the name of the sequence responsible for regulating the trp operon through attenuation?
- Multiple Choice
If tryptophan levels are low, attenuation does what to the trp operon?
- Open QuestionIn this chapter, we focused on the regulation of gene expression in bacteria. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions?How do we know that the trp operon is a repressible control system, in contrast to the lac operon, which is an inducible control system?
- Open Question
Transcriptional regulation of operon gene expression involves the interaction of molecules with one another and of regulatory molecules with segments of DNA. In this context, define and give an example of each of the following:
attenuation - Open Question
Transcriptional regulation of operon gene expression involves the interaction of molecules with one another and of regulatory molecules with segments of DNA. In this context, define and give an example of each of the following:
corepressor - Open Question
Identify similarities and differences between an inducible operon and a repressible operon in terms of
the transcription-regulating DNA sequences. - Open Question
Identify similarities and differences between an inducible operon and a repressible operon in terms of
the presence and action of allosteric regulatory molecules. - Open Question
Identify similarities and differences between an inducible operon and a repressible operon in terms of
the organization of structural genes of the operon. - Open Question
Is attenuation the product of an allosteric effect? Is attenuation the result of a transcriptional or a translational activity? Explain your answers.
- Open Question
The trpL region contains four repeated DNA sequences that lead to the formation of stem-loop structures in mRNA. What are these stem-loop structures, and how do they affect transcription of the structural genes of the trp operon?
- Open Question
Explain the circumstances under which attenuation of operon gene expression is advantageous to a bacterial organism. Would you expect attenuation to be found in a single-celled eukaryote? In a multicelled eukaryote?
- Open QuestionDescribe the role of attenuation in the regulation of tryptophan biosynthesis.
- Open QuestionAttenuation of the trp operon was viewed as a relatively inefficient way to achieve genetic regulation when it was first discovered in the 1970s. Since then, however, attenuation has been found to be a relatively common regulatory strategy. Assuming that attenuation is a relatively inefficient way to achieve genetic regulation, what might explain its widespread occurrence?