What is the likely effect of each of the following mutations of the trpL region on attenuation control of trp operon gene transcription? Explain your reasoning. Two nucleotides are inserted into the trpL region immediately after the polypeptide stop codon.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
12. Gene Regulation in Prokaryotes
Tryptophan Operon and Attenuation
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Tryptophan regulates the trp operon by doing what?
A
Activating the operon and synthesizing more tryptophan
B
Activating the operon and breaking down tryptophan
C
Repressing the operon and inhibiting further tryptophan synthesis
D
Repressing the operon and inhibiting breakdown of tryptophan

1
Understand the role of the trp operon: The trp operon is a group of genes used by bacteria to synthesize tryptophan when it is not available in the environment.
Identify the mechanism of regulation: The trp operon is regulated by a repressor protein that binds to the operator region of the operon.
Recognize the role of tryptophan: Tryptophan acts as a corepressor, meaning it binds to the repressor protein, enabling it to attach to the operator and block transcription.
Determine the effect of tryptophan presence: When tryptophan levels are high, it binds to the repressor, activating it to repress the operon, thus inhibiting further synthesis of tryptophan.
Conclude the regulatory outcome: The presence of tryptophan represses the operon, preventing the synthesis of enzymes needed for tryptophan production, thereby conserving resources.
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