13. Mendelian Genetics
Sex-Linked Inheritance
- Multiple ChoiceHemophilia is an X-linked disorder. The daughter of a father with hemophilia and a carrier mother has a __________ probability of having hemophilia.
- Multiple Choice
Wild type fruit flies have red eyes. A white-eyed female fly is crossed with a red-eyed male fly. All of the females from the cross are red-eyed and all of the males, white-eyed. What type of inheritance pattern is this?
- Multiple Choice
When Thomas Hunt Morgan crossed red-eyed F1 generation flies to each other, the F2 generation included both red- and white-eyed flies. Remarkably, all the white-eyed flies were male. What was the explanation for this result?
- Open Question
The following pedigree is for the X-linked-recessive trait for color blindness. Using XN for the normal allele and Xn for the color blindness allele, fill in the top half of the boxes/circles with the genotype. Also, fill in the bottom half of the boxes/circles with the phenotype (Normal vision or color blind). If it is impossible to know for certain a specific allele in the genotype, then place a '?' to represent the allele that is in question.
- Multiple ChoiceWhat is the probability that a human male will inherit an X-linked recessive allele from his father?
- Multiple ChoiceWhich of the following results of Thomas Hunt Morgan's experiments with white-eyed mutant flies was unexpected in light of Mendelian genetics?
- Multiple ChoiceFor an X-linked trait, it is the contribution of __________ that determines whether a son will display the trait.
- Multiple ChoiceIf a woman is heterozygous for a recessive sex-linked allele and her husband has the dominant allele, which one of the following is true about the probabilities for their children?
- Multiple ChoiceIn werewolves (hypothetically), the pointy ear allele (P) is dominant over the round ear allele (p). The gene for ear shape is on the X chromosome. (Sex determination in werewolves is the same as for "other" humans.) A certain female werewolf has pointy ears even though her father had round ears. What percentage of her sons will have round ears if she mates with a werewolf with round ears?
- Multiple ChoiceA woman is red-green color-blind. What can we conclude, if anything, about her father?
- Multiple ChoiceA woman is a carrier for red-green color blindness, a sex-linked trait. Her husband is normal (not color-blind) for this trait. What are the chances that their newborn daughter will be red-green color-blind?
- Multiple ChoiceDuchenne muscular dystrophy is caused by a sex-linked recessive allele. Its victims are almost invariably boys, who usually die before the age of 20. Why is this disorder almost never seen in girls?
- Multiple ChoiceConsider a woman who is a carrier of a recessive X-linked allele for hemophilia. Which of the following possibilities could explain the presence of the hemophilia allele in her genotype?
- Multiple ChoiceIn a certain fish, fin rays (supporting structures for the fins) can be either bony or soft in adult fish. Sex linkage in a fish is similar to that in humans. What evidence would most strongly support the idea that the ray locus is on the X chromosome?
- Multiple ChoiceX-linked genes differ from Y-linked genes in which of the following ways?