Gene G recombines with gene T at a frequency of 7%, and gene G recombines with gene R at a frequency of 4%.
Draw two possible genetic maps for these three genes, and identify the recombination frequencies predicted for each map.
4. Genetic Mapping and Linkage
Mapping Genes
- Open Question
- Multiple Choice
The genetic distances between three genes (ab, nm, kf) were determined using a two-point mapping cross. Determine the sequence of the three genes.
- Multiple Choice
True or False:Recombination frequencies are never greater than 50%
- Multiple Choice
Using the following data collected from a test cross, calculate the recombination frequency.
- Open Question
In a diploid species of plant, the genes for plant height and fruit shape are syntenic and separated by 18 m.u. Allele D produces tall plants and is dominant to d for short plants, and allele R produces round fruit and is dominant to r for oval fruit.
Give the same information for a plant with the genotype Dr/dR. - Open Question
Genes A, B, and C are linked on a chromosome and found in the order A–B–C. Genes A and B recombine with a frequency of 8%, and genes B and C recombine at a frequency of 24%. For the cross a⁺b⁺c/abc⁺×abc/abc, predict the frequency of progeny genotypes. Assume interference is zero.
- Open Question
Gene G recombines with gene T at a frequency of 7%, and gene G recombines with gene R at a frequency of 4%.
Assuming that organisms with any desired genotype are available, propose a genetic cross whose result could be used to determine which of the proposed genetic maps is correct. - Open Question
Genes A, B, C, D, and E are linked on a chromosome and occur in the order given.
The test cross indicates the genes recombine with a frequency of 28%. If 1000 progeny are produced by this test cross, determine the number of progeny in each outcome class. - Open Question
Genes A, B, C, D, and E are linked on a chromosome and occur in the order given.
Previous genetic linkage crosses have determined that recombination frequencies are 6% for genes A and B, 4% for genes B and C, 10% for genes C and D, and 11% for genes D and E. The sum of these frequencies between genes A and E is 31%. Why does the recombination distance between these genes as determined by adding the intervals between adjacent linked genes differ from the distance determined by the test cross? - Open QuestionColored aleurone in the kernels of corn is due to the dominant allele R. The recessive allele r, when homozygous, produces colorless aleurone. The plant color (not the kernel color) is controlled by another gene with two alleles, Y and y. The dominant Y allele results in green color, whereas the homozygous presence of the recessive y allele causes the plant to appear yellow. In a testcross between a plant of unknown genotype and phenotype and a plant that is homozygous recessive for both traits, the following progeny were obtained:colored, green 88colored, yellow 12colorless, green 8colorless, yellow 92Explain how these results were obtained by determining the exact genotype and phenotype of the unknown plant, including the precise arrangement of the alleles on the homologs.