13. Gene Regulation in Eukaryotes

What is the role of imprinting in human genetic disorders?

In this chapter, we focused on epigenetic modifications to the genome that regulate gene expression. Several mechanisms are involved, and epigenetic control of gene expression is important in development, cancer, and modulating the genomic response to environmental factors. From the explanations given in the chapter,

How does an environmental factor like stress generate a response that is transmitted from generation to generation?

Chromosomal regions that form heterochromatin contain:

Which of the following are examples of epigenetic marks?

CpG islands are defined as which of the following?

Which of the following terms is associated with closed chromatin?

In this chapter, we focused on epigenetic modifications to the genome that regulate gene expression. Several mechanisms are involved, and epigenetic control of gene expression is important in development, cancer, and modulating the genomic response to environmental factors. From the explanations given in the chapter,

What is the evidence that epigenetic changes are involved in cancer?

In this chapter, we focused on epigenetic modifications to the genome that regulate gene expression. Several mechanisms are involved, and epigenetic control of gene expression is important in development, cancer, and modulating the genomic response to environmental factors. From the explanations given in the chapter,

How do we know how methylation of promoters silences gene expression?

In this chapter, we focused on how eukaryotic gene expression is regulated posttranscriptionally. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter:

How do we know that microRNAs negatively regulate target mRNAs?

Write a short essay describing how epigenetic changes in cancer cells contribute to the development and maintenance of cancers.

What is meant by the term chromatin remodeling? Describe the importance of this process to transcription.