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Multiple Choice
Clonal selection:
A
Implies that each individual lymphocyte produces a single antibody.
B
Describes how the adaptive immune system can produce millions of different antibodies.
C
Depends on an antibody recognizing a specific epitope.
D
Is based on random naive B cells proliferating and differentiating.
Verified step by step guidance
1
Understand the concept of clonal selection: It is a fundamental principle of the adaptive immune system, where each B cell (a type of lymphocyte) produces a unique antibody that can bind to a specific antigen.
Recognize that clonal selection explains the diversity of antibodies: The immune system can produce millions of different antibodies, each specific to a different epitope (the part of an antigen that is recognized by the immune system).
Identify the role of naive B cells: Naive B cells are those that have not yet encountered their specific antigen. They circulate in the body until they bind to an antigen that matches their antibody.
Explore the process of proliferation and differentiation: Once a naive B cell binds to its specific antigen, it is activated and undergoes clonal expansion, where it proliferates and differentiates into plasma cells and memory B cells.
Connect the concept to immune response: Plasma cells produce large amounts of antibodies to neutralize the antigen, while memory B cells provide long-term immunity by remembering the specific antigen for faster response upon future exposure.