Open Question
In 1884, Elie Metchnikoff observed cells collected around a splinter inserted in a sea star embryo. This was the discovery of
a. blood cells.
b. sea stars.
c. phagocytosis.
d. immunity.
e. none of the above
19. Innate Immunity
Phagoctytosis
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Which of the following statements about phagocytosis is incorrect?
A
Digestion of the pathogen occurs in the phagolysosome.
B
Cells capable of phagocytosis have receptors that recognize C3b proteins or antibodies bound to the pathogen.
C
Cells capable of phagocytosis move toward the infected area of the body via chemotaxis.
D
Macrophages die after phagocytosis of a pathogen while neutrophils regenerate and survive.
Verified step by step guidance1
Understand the process of phagocytosis: Phagocytosis is a cellular process where cells, such as macrophages and neutrophils, engulf and digest pathogens or particles.
Identify the role of phagolysosome: During phagocytosis, the engulfed pathogen is enclosed in a vesicle called a phagosome, which then fuses with a lysosome to form a phagolysosome where digestion occurs.
Recognize the function of receptors: Cells capable of phagocytosis have receptors that can recognize opsonins like C3b proteins or antibodies that are bound to pathogens, facilitating their engulfment.
Understand chemotaxis: Phagocytic cells move toward the site of infection through chemotaxis, which is the movement in response to chemical signals released by pathogens or damaged tissues.
Clarify the survival of phagocytes: Typically, neutrophils die after phagocytosis, often forming pus, while macrophages can survive and continue to phagocytize multiple pathogens. The statement that macrophages die and neutrophils regenerate is incorrect.
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