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Multiple Choice
Which of the following statements about the complement system is true?
A
There are many methods of triggering the complement system.
B
There are many immune responses triggered by the complement system.
C
All triggers of the complement system lead to the formation of C3 convertase.
D
C3a and C3b result in different immune response for the complement system.
E
All of the above are true.
Verified step by step guidance
1
Understand the complement system: The complement system is a part of the immune system that enhances the ability of antibodies and phagocytic cells to clear pathogens and damaged cells, promote inflammation, and attack the pathogen's cell membrane.
Identify the triggers: The complement system can be activated through several pathways, including the classical pathway, the lectin pathway, and the alternative pathway. Each pathway involves different molecules and mechanisms to initiate the complement cascade.
Recognize the formation of C3 convertase: Regardless of the pathway that triggers the complement system, they all converge at the formation of C3 convertase, which is crucial for the subsequent steps in the complement cascade.
Differentiate the roles of C3a and C3b: C3 convertase cleaves C3 into C3a and C3b. C3a acts as an anaphylatoxin, promoting inflammation, while C3b acts as an opsonin, marking pathogens for phagocytosis and further activating the complement cascade.
Evaluate the statement: Given the understanding of the complement system, all the provided statements are true, as they accurately describe the mechanisms and outcomes of complement activation.