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Multiple Choice
Which of the following processes is the first event to take place in translation?
A
Base pairing of charged methionine-tRNA to AUG of the messenger RNA.
B
Binding of the larger ribosomal subunit to smaller ribosomal subunits.
C
The ribosome reaches a stop codon.
D
The small subunit of the ribosome recognizes and attaches to the mRNA.
Verified step by step guidance
1
Understand the process of translation, which is the synthesis of proteins from mRNA templates. It involves initiation, elongation, and termination phases.
Focus on the initiation phase of translation, which is the first step where the components necessary for protein synthesis come together.
Identify the key components involved in the initiation of translation: mRNA, the small ribosomal subunit, the initiator tRNA (charged with methionine), and the larger ribosomal subunit.
Recognize that the first event in translation initiation is the binding of the small ribosomal subunit to the mRNA. This is crucial for setting the reading frame for translation.
Note that the small ribosomal subunit scans the mRNA to find the start codon (AUG), where the initiator tRNA with methionine will base pair, setting the stage for the larger ribosomal subunit to join and form the complete ribosome.