Multiple Choice
The tRNA for which amino acid is the first to enter the ribosome?
15. Central Dogma & Gene Regulation
Steps of Translation
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What is the function of the release factor during translation?
A
It binds to the stop codon in the A site in place of a tRNA.
B
It releases the amino acid from its tRNA to allow the amino acid to be added to the growing polypeptide.
C
It supplies a source of energy for termination of translation and the release of the polypeptide.
D
It releases the ribosome from the rough endoplasmic reticulum and allows the polypeptide to enter the cytosol.
Verified step by step guidance1
Understand the process of translation: Translation is the process by which ribosomes synthesize proteins using mRNA as a template. It involves initiation, elongation, and termination phases.
Identify the role of the release factor: During the termination phase of translation, the release factor is a protein that recognizes stop codons on the mRNA strand.
Recognize the interaction with the ribosome: The release factor binds to the stop codon present in the A site of the ribosome, where normally a tRNA would bind during elongation.
Understand the function of the release factor: Once bound to the stop codon, the release factor facilitates the hydrolysis of the bond between the polypeptide chain and the tRNA in the P site, effectively releasing the newly synthesized polypeptide.
Clarify the outcome of release factor action: The action of the release factor leads to the disassembly of the translation complex, allowing the ribosome subunits, mRNA, and release factor to dissociate and be recycled for future rounds of translation.
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