Table of contents

1. Introduction to Microbiology3h 22m
2. Disproving Spontaneous Generation1h 18m
3. Chemical Principles of Microbiology3h 38m
4. Water1h 28m
5. Molecules of Microbiology2h 23m
6. Cell Membrane & Transport3h 28m
7. Prokaryotic Cell Structures & Functions5h 52m
8. Eukaryotic Cell Structures & Functions2h 18m
9. Microscopes2h 46m
10. Dynamics of Microbial Growth4h 36m
11. Controlling Microbial Growth4h 10m
12. Microbial Metabolism5h 16m
13. Photosynthesis2h 31m
14. DNA Replication2h 25m
15. Central Dogma & Gene Regulation7h 14m
16. Microbial Genetics4h 44m
17. Biotechnology3h 0m
18. Viruses, Viroids, & Prions4h 56m
19. Innate Immunity7h 15m
20. Adaptive Immunity7h 14m
21. Principles of Disease6h 57m

15. Central Dogma & Gene Regulation

Eukaryotic Chromatin Modifications

Microbiology

15. Central Dogma & Gene Regulation

Eukaryotic Chromatin Modifications

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Multiple Choice

Transcriptional repression by methylation of DNA involves the methylation of which nucleotide?

Adenine.

Uracil.

Cytosine.

Thymine.

Guanine.

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Verified step by step guidance

Understand the concept of DNA methylation: DNA methylation is a biochemical process involving the addition of a methyl group to the DNA molecule, typically at the cytosine base in the context of CpG dinucleotides.

Recognize the role of methylation in transcriptional repression: Methylation of cytosine can lead to transcriptional repression by altering the interaction of DNA with transcription factors and other proteins, thereby affecting gene expression.

Identify the nucleotide involved in methylation: In eukaryotes, cytosine is the nucleotide that is commonly methylated, particularly in CpG islands, which are regions of the genome with a high frequency of cytosine and guanine bases.

Consider the options provided: Review the list of nucleotides given in the problem (Adenine, Uracil, Cytosine, Thymine, Guanine) and recall that cytosine is the correct nucleotide involved in DNA methylation.

Conclude with the correct answer: Based on the understanding of DNA methylation and its role in transcriptional repression, confirm that cytosine is the nucleotide that undergoes methylation in this context.