Table of contents

1. Introduction to Microbiology3h 22m
2. Disproving Spontaneous Generation1h 18m
3. Chemical Principles of Microbiology3h 38m
4. Water1h 28m
5. Molecules of Microbiology2h 23m
6. Cell Membrane & Transport3h 28m
7. Prokaryotic Cell Structures & Functions5h 52m
8. Eukaryotic Cell Structures & Functions2h 18m
9. Microscopes2h 46m
10. Dynamics of Microbial Growth4h 36m
11. Controlling Microbial Growth4h 10m
12. Microbial Metabolism5h 16m
13. Photosynthesis2h 31m
14. DNA Replication2h 25m
15. Central Dogma & Gene Regulation7h 14m
16. Microbial Genetics4h 44m
17. Biotechnology3h 0m
18. Viruses, Viroids, & Prions4h 56m
19. Innate Immunity7h 15m
20. Adaptive Immunity7h 14m
21. Principles of Disease6h 57m

15. Central Dogma & Gene Regulation

Eukaryotic Chromatin Modifications

Microbiology

15. Central Dogma & Gene Regulation

Eukaryotic Chromatin Modifications

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Multiple Choice

Which of the following causes transcription to be increased for a specific gene?

Histones in that region are deacetylated.

DNA is methylated in the regulatory region of the gene.

Histones in that region are acetylated.

The chromatin structure is tightly packed.

B and D.

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Verified step by step guidance

Understand the role of histones in gene expression: Histones are proteins that help package DNA into chromatin. Their acetylation status can influence transcription levels.

Learn about histone acetylation: Acetylation of histones typically leads to a more relaxed chromatin structure, allowing transcription machinery better access to DNA, thus increasing transcription.

Explore DNA methylation: Methylation of DNA, especially in regulatory regions, often suppresses gene expression by preventing transcription factors from binding.

Examine chromatin structure: Tightly packed chromatin (heterochromatin) is generally associated with reduced transcription, while loosely packed chromatin (euchromatin) is associated with increased transcription.

Apply this knowledge to the options: Histone acetylation increases transcription, while deacetylation, DNA methylation, and tightly packed chromatin generally decrease transcription.