If a gene encoding a bacterial transpeptidase enzyme undergoes mutation, which of the following antimicrobials may no longer be effective against the mutated bacterium?
a. Macrolides
b. Polypeptide drugs
c. Tetracyclines
d. Penicillins
e. Quinolones

Which of the following antimicrobial properties would be the most crucial to consider in developing a new antimicrobial? (NCLEX/HESI/TEAS)

a. Selective toxicity

b. Ease of administration

c. Lack of drug interactions

d. Long half-life

e. The drug’s capacity to be bactericidal

A broad-spectrum drug is best described as

a. bactericidal against a wide range of species.

b. bacteriostatic against a wide range of species.

c. effective against a wide range of species.

d. empiric therapy.

e. selectively toxic.

A patient who is not a healthcare worker is diagnosed with C. difficile pseudomembranous colitis. What most likely led to this infection? (NCLEX/HESI/TEAS)

a. The patient was recently treated with a bacteriostatic drug.

b. The patient was recently treated with a broad-spectrum drug.

c. The patient was treated with a bactericidal drug.

d. The patient recently became immune compromised and therefore had an increased risk for infection.

e. The patient was recently exposed to someone with an active C. difficile infection.

Assume a bacterium makes beta-lactamase. Could you still use a glycopeptide drug to treat an infection caused by this bacterium? Explain your reasoning.

Which of the following disinfectants acts against cell membranes?

a. phenol

b. peracetic acid

c. silver nitrate

d. glutaraldehyde

Which antimicrobial chemical has been used to sterilize spacecraft?

a. phenol

b. alcohol

c. heavy metal

d. ethylene oxide

Which class of surfactant is most soluble in water?

a. quaternary ammonium compounds

b. alcohols

c. soaps

d. peracetic acids

Which of the following substances or processes kills microorganisms on laboratory surfaces?

a. antiseptics

b. disinfectants

c. degermers

d. pasteurization