Table of contents

1. Introduction to Microbiology3h 22m
2. Disproving Spontaneous Generation1h 18m
3. Chemical Principles of Microbiology3h 38m
4. Water1h 28m
5. Molecules of Microbiology2h 23m
6. Cell Membrane & Transport3h 28m
7. Prokaryotic Cell Structures & Functions5h 52m
8. Eukaryotic Cell Structures & Functions2h 18m
9. Microscopes2h 46m
10. Dynamics of Microbial Growth4h 36m
11. Controlling Microbial Growth4h 10m
12. Microbial Metabolism5h 16m
13. Photosynthesis2h 31m
14. DNA Replication2h 25m
15. Central Dogma & Gene Regulation7h 14m
16. Microbial Genetics4h 44m
17. Biotechnology3h 0m
18. Viruses, Viroids, & Prions4h 56m
19. Innate Immunity7h 15m
20. Adaptive Immunity7h 14m
21. Principles of Disease6h 57m

20. Adaptive Immunity

Immune Tolerance

Microbiology

20. Adaptive Immunity

Immune Tolerance

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Multiple Choice

The most important function of peripheral tolerance is to:

Eliminate mature B & T lymphocytes that bypassed central tolerance from reacting to self-cells.

Eliminate inactive B & T lymphocytes from peripheral blood.

Eliminate self-reacting B & T lymphocytes before they enter central tolerance.

Eliminate mature B & T lymphocytes from the bone marrow.

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Verified step by step guidance

Understand the concept of peripheral tolerance: Peripheral tolerance is a mechanism that prevents immune cells from attacking the body's own tissues after they have matured and left the central lymphoid organs.

Differentiate between central and peripheral tolerance: Central tolerance occurs in the thymus and bone marrow, where immature lymphocytes are eliminated if they react to self-antigens. Peripheral tolerance occurs after lymphocytes have matured and are in circulation.

Identify the role of peripheral tolerance: Peripheral tolerance is crucial for eliminating mature B and T lymphocytes that have escaped central tolerance and could potentially react to self-cells, preventing autoimmune responses.

Consider the options provided: Evaluate each option based on the understanding of peripheral tolerance. The correct function should align with the prevention of self-reactive mature lymphocytes from causing harm.

Select the correct answer: Based on the understanding that peripheral tolerance eliminates mature B and T lymphocytes that bypassed central tolerance, choose the option that accurately describes this function.