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Multiple Choice
In which of the steps of aerobic and anaerobic cellular respiration does substrate-level phosphorylation occur? a) In glycolysis only. b) In the Krebs cycle only. c) In the electron transport chain only. d) In both glycolysis and the Krebs cycle. e) In both the Krebs cycle and the electron transport chain.
A
In glycolysis only.
B
In the Krebs cycle only.
C
In the electron transport chain only.
D
In both glycolysis and the Krebs cycle.
E
In both the Krebs cycle and the electron transport chain.
Verified step by step guidance
1
Understand the concept of substrate-level phosphorylation: It is a type of metabolic reaction that results in the formation of ATP by the direct transfer of a phosphate group to ADP from a reactive intermediate.
Identify the stages of cellular respiration: Cellular respiration consists of glycolysis, the Krebs cycle (also known as the citric acid cycle), and the electron transport chain.
Analyze glycolysis: During glycolysis, substrate-level phosphorylation occurs when a phosphate group is transferred from a high-energy substrate molecule to ADP, forming ATP. This happens twice per glucose molecule.
Examine the Krebs cycle: In the Krebs cycle, substrate-level phosphorylation occurs when a phosphate group is transferred to GDP (or ADP) to form GTP (or ATP) in one of the cycle's steps.
Consider the electron transport chain: The electron transport chain primarily involves oxidative phosphorylation, not substrate-level phosphorylation, as ATP is generated through a proton gradient and ATP synthase activity.