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Multiple Choice
Antigen presenting cells, including dendritic cells in lymph nodes, are observed to bind T cells on their surfaces. If the dendritic cell is presenting harmful antigens on its surface and creating co-stimulatory molecules, what will happen to the T cells that bind to the dendritic cell?
A
The naive T cells that bind the dendritic cell will activate and form effector T cells.
B
The cytotoxic T cells which bind the dendritic cell will signal the dendritic cell to undergo apoptosis.
C
The anergic T cells which bind the dendritic cell will undergo apoptosis.
D
The helper T cells that bind the dendritic cell will deactivate and become naive T cells.
Verified step by step guidance
1
Understand the role of antigen-presenting cells (APCs): APCs, such as dendritic cells, present antigens to T cells to initiate an immune response. They display antigens on their surface using major histocompatibility complex (MHC) molecules.
Identify the types of T cells involved: T cells can be categorized into different types, including naive T cells, cytotoxic T cells, anergic T cells, and helper T cells, each with specific functions in the immune response.
Consider the activation of naive T cells: When naive T cells bind to a dendritic cell presenting harmful antigens along with co-stimulatory signals, they become activated and differentiate into effector T cells, which are capable of responding to the antigen.
Examine the role of cytotoxic T cells: Cytotoxic T cells, upon recognizing antigens presented by dendritic cells, can induce apoptosis in the target cells, including the dendritic cells if they are deemed harmful.
Analyze the response of anergic and helper T cells: Anergic T cells, which are non-responsive, may undergo apoptosis if they bind to the dendritic cell. Helper T cells, on the other hand, typically become activated rather than deactivated when they encounter a dendritic cell presenting antigens with co-stimulatory signals.