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Multiple Choice
Alternative RNA splicing has been estimated to occur in more than 95% of multi-exon genes. Which of the following is not an evolutionary advantage of alternative RNA splicing?
A
Alternative RNA splicing increases diversity without increasing genome size.
B
Different protein variants can be expressed by the same gene in different tissues.
C
Alternative RNA splicing creates shorter mRNA transcripts.
D
Different protein variants can be expressed by the same gene during different stages of development.
Verified step by step guidance
1
Understand the concept of alternative RNA splicing: It is a process by which different forms of mature mRNA (messenger RNA) are generated from the same gene. This allows a single gene to code for multiple proteins.
Identify the evolutionary advantages of alternative RNA splicing: It increases protein diversity without the need for additional genes, allows for tissue-specific protein expression, and enables different protein variants to be produced at different developmental stages.
Analyze the given options: The first three options describe known advantages of alternative RNA splicing, such as increasing diversity without increasing genome size, allowing tissue-specific expression, and enabling stage-specific expression.
Evaluate the option 'Alternative RNA splicing creates shorter mRNA transcripts': Consider whether this is an advantage. While alternative splicing can result in shorter transcripts, this is not inherently an evolutionary advantage.
Conclude that the option 'Alternative RNA splicing creates shorter mRNA transcripts' does not describe an evolutionary advantage, as the primary benefits of alternative splicing are related to protein diversity and functional adaptability, not transcript length.