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Multiple Choice
Lipid A is the toxic component of LPS. When pathogenic bacteria release Lipid A into the bloodstream the infected individual may experience septic shock. Lipid A represents _______.
A
A focal infection.
B
An exotoxin.
C
A systemic infection.
D
An endotoxin.
E
A and B.
F
C and D.
Verified step by step guidance
1
Understand the structure of Lipopolysaccharides (LPS): LPS is a major component of the outer membrane of Gram-negative bacteria, consisting of lipid A, a core polysaccharide, and an O-antigen.
Identify the role of Lipid A: Lipid A is the lipid component of LPS and is responsible for the toxic effects when released into the bloodstream, leading to septic shock.
Differentiate between exotoxins and endotoxins: Exotoxins are secreted by bacteria and can cause damage at distant sites, while endotoxins are part of the bacterial cell wall and are released upon cell lysis. Lipid A is classified as an endotoxin.
Clarify the concept of systemic infection: A systemic infection affects the entire body, often through the bloodstream. When Lipid A is released, it can lead to systemic effects such as septic shock.
Conclude the classification of Lipid A: Based on the definitions, Lipid A is an endotoxin and can cause systemic infection, aligning with options C and D.