Table of contents

1. Introduction to Microbiology3h 22m
2. Disproving Spontaneous Generation1h 18m
3. Chemical Principles of Microbiology3h 38m
4. Water1h 28m
5. Molecules of Microbiology2h 23m
6. Cell Membrane & Transport3h 28m
7. Prokaryotic Cell Structures & Functions5h 52m
8. Eukaryotic Cell Structures & Functions2h 18m
9. Microscopes2h 46m
10. Dynamics of Microbial Growth4h 36m
11. Controlling Microbial Growth4h 10m
12. Microbial Metabolism5h 16m
13. Photosynthesis2h 31m
14. DNA Replication2h 25m
15. Central Dogma & Gene Regulation7h 14m
16. Microbial Genetics4h 44m
17. Biotechnology3h 0m
18. Viruses, Viroids, & Prions4h 56m
19. Innate Immunity7h 15m
20. Adaptive Immunity7h 14m
21. Principles of Disease6h 57m

14. DNA Replication

Leading & Lagging DNA Strands

Microbiology

14. DNA Replication

Leading & Lagging DNA Strands

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Multiple Choice

Below is a close-up of the portion of a DNA replication bubble.

Helicase is shown as a yellow triangle currently moving from left to right. Based on what you know about the creation of new DNA during replication, which is the lagging strand and why?

A is the lagging strand, as DNA is always synthesized in the 5' to 3' manner.

B is the lagging strand, as DNA is always synthesized in the 5' to 3' manner.

A is the lagging strand, as DNA is always synthesized in the 3' to 5' manner.

B is the lagging strand, as DNA is always synthesized in the 3' to 5' manner.

It is impossible to tell, with the information provided.

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Verified step by step guidance

Understand that DNA replication involves the synthesis of new DNA strands complementary to the original template strands.

Recognize that DNA polymerase can only add nucleotides in the 5' to 3' direction, which is crucial for determining the leading and lagging strands.

Identify the direction of the helicase movement, which is from left to right in the image, unwinding the DNA double helix.

Determine the orientation of the template strands: Strand A is 5' to 3' from left to right, and Strand B is 3' to 5' from left to right.

Conclude that Strand A is the lagging strand because the new DNA must be synthesized in short segments (Okazaki fragments) in the 5' to 3' direction, opposite to the direction of the replication fork movement.

5:15m

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Struggling with Microbiology?

Below is a close-up of the portion of a DNA replication bubble.Helicase is shown as a yellow triangle currently moving from left to right. Based on what you know about the creation of new DNA during replication, which is the lagging strand and why?

Watch next

Leading & Lagging DNA Strands practice set

Below is a close-up of the portion of a DNA replication bubble.

Helicase is shown as a yellow triangle currently moving from left to right. Based on what you know about the creation of new DNA during replication, which is the lagging strand and why?