Multiple Choice
Why is DNA methylation important in DNA replication?
14. DNA Replication
DNA Polymerases
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What is DNA methylation?
A
The addition of ethyl groups (-CH2-CH3) to the sugar-phosphate backbone of DNA.
B
The addition of ethyl groups (-CH2-CH3) to the adenine and cytosine bases of DNA.
C
The addition of methyl groups (-CH3) to the sugar-phosphate backbone of DNA.
D
The addition of methyl groups (-CH3) to the adenine and cytosine bases of DNA.
Verified step by step guidance1
Understand that DNA methylation is a biochemical process involving the addition of a methyl group (-CH3) to DNA.
Recognize that this process typically occurs at specific sites on the DNA molecule, particularly at the cytosine bases in the context of CpG dinucleotides.
Note that DNA methylation can also occur at adenine bases, although this is less common in eukaryotes and more prevalent in prokaryotes.
Acknowledge that DNA methylation plays a crucial role in regulating gene expression, as it can suppress gene transcription when present in gene promoter regions.
Differentiate between methylation and other similar processes, such as ethylation, to avoid confusion with the addition of ethyl groups (-CH2-CH3), which is not a typical modification in DNA methylation.
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