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Multiple Choice
Which of the following statements is TRUE for BOTH P-type ATPases and ABC transporters?
A
They each have two ATP-binding protein domains.
B
They both contain a phosphorylated Asp residue.
C
They both are examples of multi-drug resistant proteins that pump toxins out of the cell.
D
They are both dependent on the presence of ATP.
E
They both require ATP binding before substrate binding and transport.
Verified step by step guidance
1
Understand the function of P-type ATPases: These are a class of transport proteins that use ATP to transport ions across membranes, typically involving phosphorylation of an aspartate residue.
Understand the function of ABC transporters: These are a large family of proteins that transport various molecules across membranes using ATP binding and hydrolysis.
Identify the common feature: Both P-type ATPases and ABC transporters require ATP to function, which is a key aspect of their mechanism.
Analyze the options: Evaluate each statement to determine which one correctly describes a feature shared by both P-type ATPases and ABC transporters.
Select the correct statement: The statement 'They are both dependent on the presence of ATP' accurately describes a shared characteristic of both types of transport proteins.