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Multiple Choice
How is the level of thyroxine in the blood regulated?
A
Thyroxine stimulates the pituitary to secrete thyroid-stimulating hormone (TSH).
B
TSH inhibits the secretion of thyroxine from the thyroid gland.
C
TSH-releasing hormone (TRH) inhibits the secretion of thyroxine by the thyroid gland.
D
Thyroxine stimulates the hypothalamus to secrete TRH.
E
High levels of T3 and T4 inhibit the secretion of TRH and TSH.
Verified step by step guidance
1
Begin by understanding the role of thyroxine (T4) and triiodothyronine (T3) in the body. These hormones are produced by the thyroid gland and are crucial for regulating metabolism.
Recognize the feedback loop involved in regulating these hormones. High levels of T3 and T4 in the blood signal the hypothalamus and pituitary gland to reduce the production of TRH (thyrotropin-releasing hormone) and TSH (thyroid-stimulating hormone).
Understand the role of TRH and TSH in this process. TRH is produced by the hypothalamus and stimulates the pituitary gland to release TSH. TSH then stimulates the thyroid gland to produce T3 and T4.
Identify the inhibitory effect of high levels of T3 and T4. When these hormone levels are high, they inhibit the secretion of TRH and TSH, reducing further production of thyroid hormones and maintaining balance.
Consider the overall feedback mechanism: This is a negative feedback loop where the increase in thyroid hormones leads to a decrease in the signals that stimulate their production, thus maintaining homeostasis in the body.