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Multiple Choice
IP3 (inositol trisphosphate) acts by __________.
A
activating cAMP
B
phosphorylating signal receptors
C
activating PIP2
D
activating DAG
E
opening Ca2+ channels
Verified step by step guidance
1
Understand the role of IP3 (inositol trisphosphate) in cellular signaling. IP3 is a secondary messenger that is involved in the transmission of signals from the cell surface to the inside of the cell.
Recognize that IP3 is produced from the cleavage of PIP2 (phosphatidylinositol 4,5-bisphosphate) by the enzyme phospholipase C. This process is part of the phosphoinositide signaling pathway.
Learn that IP3 primarily functions by binding to IP3 receptors located on the endoplasmic reticulum membrane. These receptors are ligand-gated calcium channels.
Understand that when IP3 binds to its receptor, it causes the opening of calcium channels, leading to the release of Ca2+ ions into the cytoplasm from the endoplasmic reticulum.
Recognize that the increase in cytoplasmic Ca2+ concentration can activate various cellular processes, including muscle contraction, secretion, metabolism, and cell growth.