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Multiple Choice
The M phase checkpoint ensures that all chromosomes are attached to the mitotic spindle. If this does not happen, cells would most likely be arrested in ________. a) Telophase. b) Prophase. c) G2. d) Metaphase.
A
Telophase.
B
Prophase.
C
G2.
D
Metaphase.
Verified step by step guidance
1
Understand the role of the M phase checkpoint: It ensures that all chromosomes are properly attached to the mitotic spindle before the cell proceeds with mitosis.
Recall the stages of mitosis: Prophase, Metaphase, Anaphase, and Telophase. Each stage has specific events that occur.
Identify the stage where chromosomes are aligned and attached to the spindle: This occurs during Metaphase, where chromosomes line up at the metaphase plate.
Consider what happens if chromosomes are not attached: The cell will be arrested in Metaphase to prevent errors in chromosome separation.
Conclude that the M phase checkpoint prevents progression past Metaphase until all chromosomes are correctly attached to the spindle.