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Multiple Choice
The unwinding of DNA at the replication fork causes twisting and strain in the DNA ahead of the fork, which is relieved by an enzyme called __________.
A
relievase
B
primase
C
ligase
D
helicase
E
topoisomerase
Verified step by step guidance
1
Understand the problem: The question is about the enzyme that relieves twisting and strain in DNA during replication.
Identify the role of each enzyme option: Relievase is not a standard enzyme name, primase synthesizes RNA primers, ligase joins DNA fragments, helicase unwinds DNA, and topoisomerase relieves strain.
Focus on the function of topoisomerase: Topoisomerase works by cutting the DNA, allowing it to unwind, and then resealing it, thus relieving the strain.
Relate the function to the problem: The problem describes the need to relieve twisting and strain, which matches the function of topoisomerase.
Conclude that topoisomerase is the enzyme that relieves the twisting and strain in DNA ahead of the replication fork.