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Multiple Choice
Which one of the following statements regarding DNA replication is correct?
A
Ligase assembles nucleotides into Okazaki fragments. Then polymerase joins these fragments together into a DNA strand.
B
The two strands of DNA separate, and nuclease enzymes digest one strand. Then DNA polymerase synthesizes two new strands out of the old ones.
C
The two strands separate, and each one receives a complementary strand of RNA. Then this RNA serves as a template for the assembly of many new strands of DNA.
D
Ligase separates the two strands of the DNA double helix. Then DNA polymerase synthesizes the leading strand and primase synthesizes the lagging strand.
E
Helicases separate the two strands of the double helix, and DNA polymerases then construct two new strands using each of the original strands as templates.
Verified step by step guidance
1
Understand the basic process of DNA replication: DNA replication is the process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules. This process is essential for cell division.
Identify the role of helicase: Helicase is an enzyme that unwinds the DNA double helix by breaking the hydrogen bonds between the complementary bases, allowing the two strands to separate.
Recognize the function of DNA polymerase: DNA polymerase is responsible for synthesizing new DNA strands by adding nucleotides complementary to the template strand. It works in the 5' to 3' direction.
Clarify the role of ligase: DNA ligase is an enzyme that joins Okazaki fragments on the lagging strand, sealing nicks in the sugar-phosphate backbone to create a continuous DNA strand.
Evaluate the given statements: Compare each statement with the known roles of helicase, DNA polymerase, and ligase in DNA replication to determine which statement accurately describes the process.