Table of contents

1. Introduction to Biology2h 42m
2. Chemistry3h 37m
3. Water1h 26m
4. Biomolecules2h 23m
5. Cell Components2h 26m
6. The Membrane2h 31m
7. Energy and Metabolism2h 0m
8. Respiration2h 40m
9. Photosynthesis2h 49m
10. Cell Signaling59m
11. Cell Division2h 47m
12. Meiosis2h 0m
13. Mendelian Genetics4h 44m
14. DNA Synthesis2h 27m
15. Gene Expression3h 6m
16. Regulation of Expression3h 31m
17. Viruses37m
- Viruses
  37m
18. Biotechnology2h 58m
19. Genomics17m
- Genomes
  17m
20. Development1h 5m
21. Evolution3h 1m
22. Evolution of Populations3h 53m
23. Speciation1h 37m
24. History of Life on Earth2h 6m
25. Phylogeny2h 31m
26. Prokaryotes4h 59m
27. Protists1h 12m
28. Plants1h 22m
29. Fungi36m
- Fungi
  19m
- Fungi Reproduction
  17m
30. Overview of Animals34m
- Overview of Animals
  34m
31. Invertebrates1h 2m
32. Vertebrates50m
33. Plant Anatomy1h 3m
34. Vascular Plant Transport1h 2m
- Water Potential
  1h 2m
35. Soil37m
- Soil and Nutrients
  20m
- Nitrogen Fixation
  16m
36. Plant Reproduction47m
- Flowers
  33m
- Seeds
  14m
37. Plant Sensation and Response1h 9m
38. Animal Form and Function1h 19m
39. Digestive System1h 10m
- Digestion
  1h 3m
- Blood Sugar Homeostasis
  7m
40. Circulatory System1h 49m
41. Immune System1h 12m
42. Osmoregulation and Excretion50m
- Osmoregulation and Excretion
  50m
43. Endocrine System1h 4m
- Endocrine System
  1h 4m
44. Animal Reproduction1h 2m
- Animal Reproduction
  1h 2m
45. Nervous System1h 55m
- Neurons and Action Potentials
  1h 8m
- Central and Peripheral Nervous System
  46m
46. Sensory Systems46m
- Sensory System
  46m
47. Muscle Systems23m
- Musculoskeletal System
  23m
48. Ecology3h 11m
49. Animal Behavior28m
- Animal Behavior
  28m
50. Population Ecology3h 41m
51. Community Ecology2h 46m
52. Ecosystems2h 36m
53. Conservation Biology24m
- Conservation Biology
  24m

10. Cell Signaling

Classes of Signaling Receptors

General Biology

10. Cell Signaling

Classes of Signaling Receptors

Previous problemNext problem

Struggling with General Biology?

Join thousands of students who trust us to help them ace their exams!Watch the first video

Multiple Choice

A G protein is active when __________.

GDP replaces GTP

it is bound by its ligand and transported to the nucleus

it is phosphorylated by a protein kinase

Ca²⁺ binds to a G-protein-coupled receptor

GTP is bound to it

Previous problemNext problem

Verified step by step guidance

Understand the role of G proteins in cell signaling: G proteins are molecular switches that play a crucial role in transmitting signals from outside the cell to the inside. They are involved in various signaling pathways, often associated with G-protein-coupled receptors (GPCRs).

Identify the components of a G protein: G proteins are composed of three subunits: alpha (α), beta (β), and gamma (γ). The alpha subunit is the one that binds to guanine nucleotides (GDP and GTP).

Recognize the inactive state of a G protein: In its inactive state, the G protein is bound to GDP (guanosine diphosphate). This means that the alpha subunit is associated with GDP, and the G protein is not transmitting a signal.

Determine the activation mechanism: A G protein becomes active when GDP is replaced by GTP (guanosine triphosphate) on the alpha subunit. This exchange is often triggered by the binding of a ligand to a GPCR, which causes a conformational change in the receptor and subsequently in the G protein.

Conclude the active state: Once GTP is bound to the alpha subunit, the G protein is considered active. It can then dissociate from the beta and gamma subunits and interact with other proteins or enzymes in the cell to propagate the signal, leading to a cellular response.