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Multiple Choice
Which of the following cells are part of the innate, second line of defense?
A
Cytotoxic T cells
B
B cells
C
Dendritic cells
D
Platelets
E
Macrophages
Verified step by step guidance
1
Understand the concept of the innate immune system: The innate immune system is the body's first line of defense against pathogens. It includes physical barriers like skin and mucous membranes, as well as immune cells that respond quickly to invaders.
Identify the role of macrophages: Macrophages are a type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, and cancer cells. They are a crucial component of the innate immune system's second line of defense.
Differentiate between innate and adaptive immunity: Innate immunity is non-specific and responds to pathogens in a generic way, while adaptive immunity is specific and involves the activation of lymphocytes (B cells and T cells) that target specific antigens.
Recognize the function of other cells listed: Cytotoxic T cells and B cells are part of the adaptive immune system, not the innate system. Dendritic cells, while part of the innate system, primarily function as antigen-presenting cells to activate the adaptive immune response. Platelets are involved in blood clotting and not directly in immune defense.
Conclude that macrophages are part of the innate, second line of defense: Given their role in phagocytosis and rapid response to pathogens, macrophages are indeed part of the innate immune system's second line of defense.