21. The Immune System
Clonal Selection
- Open QuestionWhich of the following is not involved in the activation of a B cell?a. antigen,b. helper T cell,c. cytokine,d. cytotoxic T cell.
- Open Question
Terrence has severe asthma and allergies, and is placed on a medication that blocks the functioning of IgE. How would this medication alleviate his symptoms?
- Multiple ChoiceHumoral immunity is provided by __________.
- Open QuestionTed finds out that he has been exposed to measles. He is concerned that he might have contracted the disease, so he goes to see his physician. The physician takes a blood sample and sends it to a lab for antibody levels and titers. The results show an elevated level and activity of IgM antibodies to rubella (measles) virus but very few IgG antibodies to the virus. Has Ted contracted the disease?
- Multiple Choice
Which of the following is NOT an organ where clonal selection occurs?
- Open QuestionMultiple ChoiceMore than one choice may apply.Which of these antibody classes is usually arranged as a pentamer?a. IgGb. IgMc IgAd. IgD
- Multiple Choice
All of the following are postulates of the clonal selection theory EXCEPT:
- Multiple Choice
Clonal selection:
- Open QuestionDefine antibody. Using an appropriately labeled diagram, describe the structure of an antibody monomer. Indicate and label variable and constant regions, heavy and light chains.
- Open Question
Match the following antibodies with the correct definition.
____IgD
____IgM
____IgG
____IgA
____IgE
a. Antibody found in secretions
b. Most common antibody; crosses the placenta
c. Antibody involved in allergies and parasitic infections
d. Pentamer and potent agglutinating agent
e. Antibody bound to the B cell plasma membrane
- Multiple Choice
Which of the following statements is FALSE?
- Open Question
Mark the following statements as true or false. If a statement is false, correct is to make a true statement.
d. Vaccinations are given to induce the production of the inflammatory response.
- Open QuestionName the five classes of immunoglobulins. Which is most likely to be found attached to a B cell membrane? Which is most abundant in plasma? Which is important in allergic responses? Which is the first Ig to be released during the primary response? Which can cross the placental barrier?
- Open QuestionHow does the formation of an antigen–antibody complex cause the elimination of an antigen?
- Open QuestionName the five antibody classes and describe where each is most likely to be found in the body.