Multiple ChoiceWhich of the following accurately characterizes our current understanding of cancer development?
Open QuestionVinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related toa. disruption of mitotic spindle formation.b. suppression of cyclin production.c. myosin denaturation and inhibition of cleavage furrow formation.d.inhibition of DNA synthesis.
Open QuestionOne difference between cancer cells and normal cells is that cancer cellsa. are unable to synthesize DNA.b. are arrested at the S phase of the cell cycle.c. continue to divide even when they are tightly packed together.d. cannot function properly because they are affected by density-dependent inhibition.
Open QuestionEvaluate each of the following defects. Which could lead to uncontrolled growth in cancer? Select True or False for each statement.T/FThe overexpression of MPF activity.T/FA nonfunctional Rb protein.T/FThe overexpression of G1 cyclin.T/FA nonfunctional E2F protein.
Open QuestionAll your cells contain proto-oncogenes, which can change into cancer-causing oncogenes. Why do cells possess such potential time bombs?