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Multiple Choice
When searching for a donor for an organ transplant, doctors try to match the __________ of the donor and recipient as closely as possible.
A
antibodies
B
blood type
C
leukocytes
D
cytokines
E
MHC proteins
Verified step by step guidance
1
Understand the role of MHC proteins: Major Histocompatibility Complex (MHC) proteins are crucial for the immune system to recognize foreign molecules. They help the body distinguish between self and non-self cells.
Recognize the importance of MHC matching: In organ transplants, matching the MHC proteins of the donor and recipient is vital to reduce the risk of organ rejection. The closer the match, the less likely the recipient's immune system will attack the transplanted organ.
Differentiate from other options: Antibodies are proteins that recognize and neutralize pathogens, blood type refers to the classification of blood based on the presence of antigens, leukocytes are white blood cells involved in immune response, and cytokines are signaling molecules in the immune system. None of these are directly involved in tissue compatibility like MHC proteins.
Consider the process of tissue typing: Before a transplant, tissue typing tests are conducted to compare the MHC proteins of the donor and recipient. This helps in selecting the most compatible donor.
Conclude with the significance of MHC in transplants: A close match in MHC proteins between donor and recipient minimizes the risk of rejection and increases the chances of a successful transplant.