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Multiple Choice
The antigen-binding sites of an antibody molecule are formed from the molecule's variable regions. Why are these regions described as variable?
A
They can change their shapes to fit different antigens.
B
They change their shapes when they bind to an antigen.
C
Their specific shapes are unimportant.
D
Their sizes vary considerably from one antibody to another.
E
The amino acid sequences of these regions vary widely among antibodies from different B cells.
Verified step by step guidance
1
Understand that antibodies are proteins produced by B cells that recognize and bind to specific antigens.
Recognize that each antibody has a unique structure that allows it to bind to a specific antigen. This specificity is due to the variable regions of the antibody.
The variable regions are located at the tips of the 'Y' shape of the antibody and are responsible for antigen binding.
These regions are described as 'variable' because the amino acid sequences in these regions differ greatly among antibodies produced by different B cells. This variability allows the immune system to recognize a vast array of antigens.
The variability in amino acid sequences leads to different three-dimensional shapes, enabling antibodies to bind specifically to different antigens.