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Multiple Choice
At what point do sister chromatids separate?
A
G1 phase
B
G2 phase
C
Metaphase
D
prophase
E
Anaphase
Verified step by step guidance
1
Understand the cell cycle phases: The cell cycle consists of interphase (G1, S, G2 phases) and the mitotic phase (M phase), which includes prophase, metaphase, anaphase, and telophase.
Identify the role of sister chromatids: Sister chromatids are identical copies of a chromosome connected by a centromere, formed during the S phase of interphase.
Review the events of mitosis: During mitosis, the cell divides its copied DNA and cytoplasm to form two new cells. Key stages include prophase, metaphase, anaphase, and telophase.
Focus on anaphase: In anaphase, the centromeres split, and the sister chromatids are pulled apart by the spindle fibers toward opposite poles of the cell.
Conclude that sister chromatids separate during anaphase, as this is the stage where they are no longer connected and move to opposite ends of the cell.