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Multiple Choice
Which of the following statements about replication origins is/are correct?
A
Bacterial chromosomes have a single origin of replication, but eukaryotic chromosomes have many origins.
B
The DNA sequence at the origin of replication is recognized by specific proteins that bind to the origin.
C
The two strands of DNA at the origin of replication are separated, creating a replication bubble.
D
Replication proceeds in both directions from each origin.
E
All of the listed responses are correct.
Verified step by step guidance
1
Understand that replication origins are specific sequences in the genome where DNA replication begins.
Recognize that bacterial chromosomes typically have a single origin of replication due to their circular DNA structure, while eukaryotic chromosomes, which are linear and larger, have multiple origins to ensure timely replication.
Identify that specific proteins, such as initiator proteins, recognize and bind to the DNA sequence at the origin of replication to initiate the replication process.
Acknowledge that the binding of these proteins causes the two strands of DNA to separate at the origin, forming a replication bubble where replication machinery can access the DNA strands.
Note that replication is bidirectional, meaning it proceeds in both directions from each origin, allowing for efficient and rapid replication of the entire DNA molecule.