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Multiple Choice
Although it contains roughly the same number of genes as the nematode genome, the human genome is thought to produce greater phenotypic diversity by means of __________.
A
post-translation addition of carbohydrates to polypeptides
B
alternate splicing of RNA transcripts
C
regulation of gene expression by miRNAs
D
post-translational cleavage of a polypeptide into active forms
E
All of the listed responses are correct.
Verified step by step guidance
1
Understand that the human genome and the nematode genome have a similar number of genes, but humans exhibit greater phenotypic diversity.
Recognize that phenotypic diversity can be increased through various mechanisms that affect gene expression and protein function.
Consider the role of alternate splicing of RNA transcripts, which allows a single gene to produce multiple protein variants by rearranging exons during mRNA processing.
Examine the regulation of gene expression by miRNAs (microRNAs), which can bind to mRNA molecules and either degrade them or inhibit their translation, thus affecting protein production.
Explore post-translational modifications, such as the addition of carbohydrates to polypeptides and cleavage of polypeptides into active forms, which can alter protein function and activity, contributing to phenotypic diversity.