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Multiple Choice
Prions are __________ that are thought to cause disease by __________.
A
RNA molecules; encoding toxic proteins
B
mutant DNA molecules; encoding toxic proteins
C
an abnormal type of capsid; dramatically enhancing the rate of viral infection
D
DNA molecules; jumping around the genome and mutating genes
E
abnormally shaped proteins; inducing similar but normally shaped proteins in the brain to adopt the abnormal form
Verified step by step guidance
1
Understand the concept of prions: Prions are infectious agents composed entirely of protein. Unlike bacteria, viruses, or fungi, prions do not contain nucleic acids (DNA or RNA).
Recognize the mechanism of prion-induced disease: Prions cause disease by inducing normal proteins in the brain to misfold into the abnormal prion form. This process leads to a chain reaction, where the misfolded proteins accumulate and disrupt normal cellular function.
Identify the correct answer choice: The problem provides multiple options, but the correct answer is that prions are abnormally shaped proteins that induce similar but normally shaped proteins in the brain to adopt the abnormal form.
Clarify why other options are incorrect: RNA molecules encoding toxic proteins, mutant DNA molecules encoding toxic proteins, abnormal capsids enhancing viral infection, and DNA molecules mutating genes do not describe the mechanism of prion action.
Summarize the key points: Prions are unique infectious agents that propagate by altering the structure of normal proteins, leading to neurodegenerative diseases. This understanding is crucial for comprehending how prion diseases differ from other infectious diseases.