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Multiple Choice
Chargaff found that for DNA __________.
A
the ratio of A to C is close to 1:1 and the ratio of G to T is close to 1:1
B
the ratio of A to G is close to 1:1 and the ratio of T to C is close to 1:1
C
A + T = G + C
D
A + T = 50% of the total bases
E
the ratio of A to T is close to 1:1 and the ratio of G to C is close to 1:1
Verified step by step guidance
1
Understand Chargaff's rules: Chargaff's rules state that in DNA, the amount of adenine (A) is approximately equal to the amount of thymine (T), and the amount of guanine (G) is approximately equal to the amount of cytosine (C). This is because A pairs with T and G pairs with C in the DNA double helix.
Identify the correct ratios: Based on Chargaff's rules, the correct ratios are A:T and G:C, both of which should be close to 1:1. This means that for every adenine, there is a thymine, and for every guanine, there is a cytosine.
Eliminate incorrect options: Review the given options and eliminate those that do not align with Chargaff's rules. For example, options suggesting A + T = G + C or A + T = 50% of the total bases do not reflect the 1:1 pairing rule.
Select the correct answer: The option stating 'the ratio of A to T is close to 1:1 and the ratio of G to C is close to 1:1' correctly reflects Chargaff's findings about DNA base pairing.
Review the concept: Remember that Chargaff's rules are fundamental to understanding the structure of DNA and the base pairing mechanism, which is crucial for DNA replication and function.