Juan has a disease in which damaged kidneys allow some of his normal plasma proteins to be removed from the blood. How might this condition affect the osmotic pressure of blood in capillaries, compared with that of the surrounding interstitial fluid? One of the symptoms of this kidney malfunction is an accumulation of excess interstitial fluid, which causes Juan's arms and legs to swell. Can you explain why this occurs?

Explain why a person who survives a myocardial infarction might need to have an artificial pacemaker implanted.

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise?Researchers used echocardiography, a sonogram of the heart, to estimate the mass of the left ventricle in current athletes, non-athletes, and ex-athletes. The data are graphed below (***meansP<0.001, and the P value comparing non-athletes and ex-athletes is >0.05). What conclusion can be drawn from the graph?

Some babies are born with a small hole in the wall between the left and right ventricles. How might this affect the oxygen content of the blood pumped out of the heart into the systemic circuit?

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise?Explain the advantage of the observed difference between current athletes and non-athletes in the graph shown here.

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise?Researchers have also observed that athletes and non-athletes have the same mean resting cardiac output, even though athletes have a far lower resting heart rate. How is this possible?

SCIENTIFIC THINKING The studies described in Module 23.6 were funded by both government agencies and major pharmaceutical and medical supply companies. NIH grants for research on heart disease total more than \$1.2 billion per year. Gather more information and form an opinion on how heart disease research should be funded, whether by private enterprises such as pharmaceutical companies, donor-supported nonprofit organizations, or government agencies. Write an essay arguing your point of view.

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise?Athletes are not the only people with enlarged hearts. Many patients with cardiovascular disease also have enlarged hearts. Suggest a cause of this enlargement.

Which chamber(s) of a human heart receive(s) and pump(s) oxygenated blood?