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Multiple Choice
A company was testing a new drug it thought would help decrease the risk of transmission of viruses from mother to fetus. In an experiment to test the compound, an investigator gave 400 pregnant female rats a small dose of the experimental drug and inoculated each with a type of virus known to cause disease in rats. At the same time, 400 other pregnant rats were given only the virus. Of the rat pups born to the females that received both the virus and the drug, 197 showed no symptoms of the disease; 205 rat pups born to the virus-only females showed symptoms. From these data, we can best conclude __________.
A
that the drug is effective and testing on humans should begin
B
nothing because no independent variable could be identified
C
nothing because no control group was used in the test of the drug
D
that the drug seems to have little effect on viral transmission at the dosage given
Verified step by step guidance
1
Identify the groups in the experiment: one group of 400 pregnant rats received the drug and the virus, while another group of 400 pregnant rats received only the virus.
Determine the outcome for each group: In the drug and virus group, 197 rat pups showed no symptoms. In the virus-only group, 205 rat pups showed symptoms.
Compare the results: The number of rat pups showing no symptoms in the drug group is 197, while the number of rat pups showing symptoms in the virus-only group is 205.
Analyze the effectiveness of the drug: Since the number of symptom-free rat pups in the drug group is not significantly higher than the number of symptomatic rat pups in the virus-only group, the drug seems to have little effect at the given dosage.
Conclude based on the analysis: The data suggests that the drug does not significantly decrease the risk of viral transmission from mother to fetus at the dosage given, indicating that further testing or dosage adjustment may be necessary before considering human trials.