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Multiple Choice
What two genes are often mutated in colon cancer?
A
ras and myoD
B
p21 and p53
C
BRCA1 and BRCA2
D
APC and myoD
E
ras and p53
Verified step by step guidance
1
Understand that colon cancer is often associated with mutations in specific genes that regulate cell growth and division.
Identify the genes commonly mutated in colon cancer. The genes ras and p53 are frequently mentioned in the context of cancer due to their roles in cell cycle regulation and apoptosis.
Recognize that the ras gene is part of a family of genes that encode proteins involved in transmitting signals within cells, which can lead to uncontrolled cell growth if mutated.
Learn that the p53 gene is known as the 'guardian of the genome' because it plays a crucial role in preventing cancer formation by repairing DNA or initiating apoptosis if the DNA damage is irreparable.
Conclude that mutations in both ras and p53 can disrupt normal cellular functions, leading to the development of colon cancer.