You are studying how a hormone affects a cell and find that when oxytocin binds the receptor, the intracellular CaCaCa2^22+^++ concentration increases. Based on this information, what could you logically conclude about this cell and hormone?

The cell uses I P 3 IP_3 I P 3 and DAG as secondary messengers.

You are studying how a hormone affects a cell and find that when oxytocin binds the receptor, the intracellular C a Ca C a 2 ^2 2 + ^+ + concentration increases. Based on this information, what could you logically conclude about this cell and hormone?

This question's about oxytocin, and it tells us that oxytocin causes the intracellular calcium concentration to increase. And knowing that, what can we reasonably conclude about this hormone and the cells that it affects? Well, when I see that calcium concentration increasing, it makes me think of that IP 3 and DAG signaling cascade, where those are the 2 second messengers used. Now specifically, it's that IP 3 molecule that causes the release of calcium into the cell, which causes a whole bunch of downstream effects. So regardless knowing that, I look down and c says the cell uses IP 3 and DAG as secondary messengers. So I'm pretty sure that's correct. I'm gonna give that one my green checkaroo, but we'll see our other options. We have a. The cell uses adenylate cyclase as a second messenger. Well, adenylate cyclase isn't a second messenger. It's an enzyme that produces the second messenger, cyclic AMP. But when we talked about the cyclic AMP cascade, we did not talk about it causing the release of calcium, at least not directly. So regardless, this has a number of problems with it. It's not my answer. Next, we have oxytocin directly interacts with the DNA of a cell. Well, directly interacting with the DNA of a cell we're talking about second messengers here. The oxytocin is gonna stay on the outside of the cell, And regardless, directly interacting with the DNA of the cell, there's no reason why I think that should directly cause an increase in calcium concentration. Lots of things wrong here. I'm crossing it out. D says both a and b are correct. Well, both a and b are incorrect, so it's not that. And so, therefore, I feel very good in saying that if we're talking about an increase in the calcium concentration in the cell, it's likely that the cell uses IP 3 and DAG as secondary messengers, and specifically that IP3 molecule is what's directly responsible for that increase in the calcium concentration. That's my answer.

You are studying how a hormone affects a cell and find that when oxytocin binds the receptor, the intracellular C a Ca C a 2 ^2 2 + ^+ + concentration increases. Based on this information, what could you logically conclude about this cell and hormone?

The cell uses I P 3 IP_3 I P 3 and DAG as secondary messengers.

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1. Introduction to Anatomy & Physiology5h 43m
2. Cell Chemistry & Cell Components12h 36m
3. Energy & Cell Processes10h 6m
4. Tissues & Histology10h 3m
5. Integumentary System2h 20m
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- Introduction to the Central Nervous System
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13. The Peripheral Nervous System1h 26m
14. The Autonomic Nervous System1h 38m
15. The Special Senses2h 41m
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16. The Endocrine System

Membrane Bound Receptors and Secondary Messengers

Anatomy & Physiology

16. The Endocrine System

Membrane Bound Receptors and Secondary Messengers

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Multiple Choice

You are studying how a hormone affects a cell and find that when oxytocin binds the receptor, the intracellular $Ca$ $^2$ $^+$ concentration increases. Based on this information, what could you logically conclude about this cell and hormone?

The cell uses adenylate cyclase as a second messenger.

Oxytocin directly interacts with the DNA of the cell.

The cell uses $IP_3$ and DAG as secondary messengers.

Both A & B are correct.

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Verified step by step guidance

Understand the role of oxytocin: Oxytocin is a hormone that typically binds to receptors on the cell surface, initiating a signaling cascade inside the cell.

Identify the signaling pathway: When oxytocin binds to its receptor, it often activates a G-protein coupled receptor (GPCR) pathway, which can lead to the production of secondary messengers.

Consider the increase in intracellular Ca^2+ concentration: An increase in intracellular calcium is often associated with the activation of the inositol trisphosphate (IP3) pathway.

Link IP3 to calcium release: IP3 is a secondary messenger that binds to receptors on the endoplasmic reticulum, causing the release of Ca^2+ into the cytoplasm.

Conclude the signaling mechanism: Since the increase in Ca^2+ is observed, it is logical to conclude that the cell uses IP3 and diacylglycerol (DAG) as secondary messengers, which are part of the phospholipase C pathway activated by GPCRs.