Explain why Avery, MacLeod, and McCarty's in vitro transformation experiment showed that DNA, but not RNA or protein, is the hereditary molecule.

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Hey, everyone. Let's take a look at this question together, Avery mcleod and mccarthy's experiment by injecting mice with heat inactivated bacteria and noninfectious bacteria proved that DNA is the transformation factor in the probable hereditary material. Which of the following statements regarding their experiment is incorrect. Is it answer choice. A violin s strain developed in the cell extract treated with protease. Answer choice B violin S strain did not develop in the cell extract treated with R N A S. Answer choice C violin S strain did not develop in the cell extract treated with DNA S or answer choice D both B and C. Let's work this problem out together to try to figure out which of the following statements regarding Avery mcleod and mccarthy's experiment is incorrect. So the purpose of Avery mcleod and mccarthy's experiment was to determine which biochemical meaning protein R N A or DNA could transform those live ourselves N two S cells. And so in their experiment, they first started off by purifying the he killed cells and then they had three sets of tubes containing different substances. And so we have our first tube which contained R N A S we have our second tube that contained DNA. And lastly our third tube which contained prote ace. And so they wanted to figure out which of the tubes containing the different substances would still be able to transform the R strain into the live S strain. And from their experiment, they were able to determine that the tubes containing R N A and protein were still able to transform those R cells into those S cells. However, DNA was not able to make that transformation. And so they were able to determine that the transformation of the S cells was triggered. Bye DNA. And we know that the tube containing DNA S is used to degrade DNA. And so the tube containing R N A and the tube containing prote ace still had that DNA, which allowed the transformation of the S cells to occur. And so looking at our answer choices, we can see that answer choice. A says that the viral S strain developed in the cell extract treated with protease, which we know is correct answer. Choice B says that the viral S strain did not develop in the cell extract treated with R N A, which we know that it did develop in the cell extract that was treated with R N A. So that is an incorrect statement which means that answer choice B virulent S strain did not develop in the cell extract treated with R N A is the correct answer. Since we know that the viral and S strain developed in the cell extract, treated with protease and R N A but not the cell extract that was treated with DNA S making answer choice. AC and D, the incorrect answers. Since answer choice A and C are both true statements. And answer choice. B is the only statement here regarding their experiment that is incorrect, making it the correct answer. I hope you found this video to be helpful. Thank you and goodbye.

Explain why Avery, MacLeod, and McCarty's in vitro transformation experiment showed that DNA, but not RNA or protein, is the hereditary molecule.

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Key Concepts

DNA as the Genetic Material

In Vitro Transformation

Exclusion of RNA and Protein