Textbook Question
For the cross Aabb × aaBb, what is the expected genotype ratio? What is the expected phenotype ratio?
Ch. 2 - Transmission Genetics
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
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Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 2, Problem 5
Two parents plan to have three children. What is the probability that the children will be two girls and one boy?
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Identify the total number of children and the desired gender combination: 3 children with exactly 2 girls and 1 boy.
Recognize that each child’s gender is an independent event with a probability of 1/2 for a girl and 1/2 for a boy.
Calculate the number of different ways to arrange 2 girls and 1 boy among 3 children using combinations: .
Determine the probability of one specific arrangement (e.g., girl, girl, boy) by multiplying the probabilities: .
Multiply the number of arrangements by the probability of one arrangement to get the total probability: .
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Basic Probability
Probability measures the likelihood of an event occurring, expressed as a number between 0 and 1. In genetics, it helps predict the chances of offspring having certain traits, such as gender, assuming each outcome is equally likely and independent.
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Binomial Probability Distribution
This distribution calculates the probability of a specific number of successes (e.g., girls) in a fixed number of independent trials (e.g., children), each with the same probability of success. It uses combinations to account for different orders of outcomes.
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Combinatorics (Permutations and Combinations)
Combinatorics involves counting the number of ways events can occur. For this problem, combinations determine how many ways two girls and one boy can be arranged among three children, which is essential for calculating the total probability.
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Related Practice
Textbook Question
In mice, black coat color is dominant to white coat color. In the pedigree shown here, mice with a black coat are represented by darkened symbols, and those with white coats are shown as open symbols. Using allele symbols B and b, determine the genotypes for each mouse.
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Textbook Question
A man, J.B., has a sister with autosomal recessive galactosemia (OMIM 230400), and his partner, S.B., has a brother with galactosemia. Galactosemia is a serious condition caused by an enzyme deficiency that prevents the metabolism of the sugar galactose. Neither J.B. nor S.B. has galactosemia, but they are concerned about the risk that a future child of theirs will have the condition. What is the probability their first child will have galactosemia?
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Textbook Question
A woman, S.R., had a maternal grandfather with hemophilia A (OMIM 306700), an X-linked recessive condition that reduces blood clotting. S.R.'s maternal grandmother and paternal grandparents are free of the condition, as are her partner, his parents, and his grandparents. S.R. has no siblings. She wants to know the chance that a son of hers will have the condition. What is that probability?
Textbook Question
A 40-year-old woman whose father had Huntington disease currently shows no symptoms of the disease. She is newly pregnant with her first child and seeks your best estimate of the chance her child will inherit the disease. What is your estimate and how did you arrive at it? (Hint: See Figure 4.11)
Textbook Question
Consider the cross AaBbCC × AABbCc.
How many different gamete genotypes can each organism produce?