Textbook Question
What aspect of DNA structure makes it possible for the proteins of nucleotide excision repair to recognize many different types of DNA damage?
(a) the polarity of each DNA strand
Ch. 15 - DNA and the Gene: Synthesis and Repair
Freeman8th EditionBiological ScienceISBN: 9780138276263
Not the one you use?Change textbookSelect a different textbook
Table of contents
- Ch. 1 - Biology: The Study of Life13
- Ch. 2 - Water and Carbon: The Chemical Basis of Life14
- Ch.3 - Protein Structure and Function10
- Ch.4 - Nucleic Acids and the RNA World10
- Ch. 5 - An Introduction to Carbohydrates10
- Ch. 6 - Lipids, Membranes, and the First Cells11
- Ch. 7 - Inside the Cell10
- Ch. 8 - Energy and Enzymes: An Introduction to Metabolism10
- Ch. 9 - Cellular Respiration and Fermentation11
- Ch. 10 - Photosynthesis12
- Ch. 11 - Cell-Cell Interactions12
- Ch. 12 - The Cell Cycle8
- Ch. 13 - Meiosis12
- Ch. 14 - Mendel and the Gene23
- Ch. 15 - DNA and the Gene: Synthesis and Repair15
- Ch. 16 - How Genes Work16
- Ch. 17 - Transcription, RNA Processing, and Translation16
- Ch. 18 - Control of Gene Expression in Bacteria16
- Ch. 19 - Control of Gene Expression in Eukaryotes12
- Ch. 20 - The Molecular Revolution: Biotechnology, Genomics, and New Frontiers15
- Ch. 21 - Genes, Development, and Evolution12
- Ch. 22 - Evolution by Natural Selection16
- Ch. 23 - Evolutionary Processes13
- Ch. 24 - Speciation15
- Ch. 25 - Phylogenies and the History of Life13
- Ch. 26 - Bacteria and Archaea15
- Ch. 27 - Diversification of Eukaryotes16
- Ch. 28 - Green Algae and Land Plants16
- Ch. 29 - Fungi18
- Ch. 30 - An Introduction to Animals9
- Ch. 31 - Protostome Animals15
- Ch. 32 - Deuterostome Animals17
- Ch. 33 - Viruses16
- Ch. 34 - Plant Form and Function16
- Ch. 35 - Water and Sugar Transport in Plants16
- Ch. 36 - Plant Nutrition13
- Ch. 37 - Plant Sensory Systems, Signals, and Responses16
- Ch. 38 - Flowering Plant Reproduction and Development16
- Ch. 39 - Animal Form and Function17
- Ch. 40 - Water and Electrolyte Balance in Animals16
- Ch. 41 - Animal Nutrition16
- Ch. 42 - Gas Exchange and Circulation16
- Ch. 43 - Animal Nervous Systems16
- Ch. 44 - Animal Sensory Systems16
- Ch. 45 - Animal Movement11
- Ch. 46 - Chemical Signals in Animals16
- Ch. 47 - Animal Reproduction and Development16
- Ch. 48 - The Immune System in Animals16
- Ch. 49 - An Introduction to Ecology15
- Ch. 50 - Behavioral Ecology16
- Ch. 51 - Population Ecology16
- Ch. 52 - Community Ecology20
- Ch. 53 - Ecosystems and Global Ecology17
- Ch. 54 - Biodiversity and Conservation Ecology18
Chapter 15, Problem 8d
What aspect of DNA structure makes it possible for the proteins of nucleotide excision repair to recognize many different types of DNA damage?
(d) the regularity of DNA's structure
Verified step by step guidance1
Understand the basic structure of DNA: DNA is composed of two strands forming a double helix, with a backbone made of sugar and phosphate groups, and nitrogenous bases (adenine, thymine, cytosine, and guanine) paired in the center.
Recognize the regularity of DNA's structure: The double helix has a consistent diameter and uniform spacing between the base pairs, which contributes to its regularity.
Learn about nucleotide excision repair: This is a DNA repair mechanism that identifies and removes damaged sections of DNA, replacing them with the correct nucleotides.
Consider how the regularity aids repair: The consistent structure of DNA allows repair proteins to easily detect irregularities or distortions caused by damage, as these deviations stand out against the uniform background.
Explore the role of repair proteins: These proteins scan the DNA for structural anomalies, and the regularity of the DNA helix makes it easier for them to identify and bind to damaged sites, facilitating the repair process.
Verified video answer for a similar problem:
This video solution was recommended by our tutors as helpful for the problem above.
Video duration:
49sWas this helpful?
Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
DNA Structure
DNA is composed of two strands forming a double helix, with a backbone of sugar-phosphate and nitrogenous bases paired in the center. This regular and predictable structure allows for consistent recognition by repair proteins, as any deviation from the norm can indicate damage.
Recommended video:
Guided course
04:41
Discovering the Structure of DNA
Nucleotide Excision Repair
Nucleotide excision repair is a DNA repair mechanism that identifies and removes damaged sections of DNA. It relies on the ability to detect irregularities in the DNA structure, such as distortions caused by chemical modifications or UV-induced lesions, to initiate repair processes.
Recommended video:
Guided course
03:20DNA Repair
DNA Damage Recognition
Proteins involved in DNA repair recognize damage by detecting structural anomalies in the DNA helix. The regularity of DNA's structure provides a baseline for these proteins to identify disruptions, enabling them to target and repair a wide range of damage types effectively.
Recommended video:
Guided course
04:01DNA Polymerases
Related Practice
Textbook Question
What aspect of DNA structure makes it possible for the proteins of nucleotide excision repair to recognize many different types of DNA damage?
(b) the antiparallel orientation of strands in the double helix
Textbook Question
What aspect of DNA structure makes it possible for the proteins of nucleotide excision repair to recognize many different types of DNA damage?
(c) the energy differences between correct and incorrect base pairs
Textbook Question
In the late 1950s, Herbert Taylor grew bean root-tip cells in a solution of radioactive thymidine (a precursor to one of the deoxyribonucleotides in DNA) and allowed them to undergo one round of DNA replication. He then transferred the cells to a solution without radioactive thymidine, allowed them to replicate again, and examined their chromosomes for the presence of radioactivity. His results are shown in the following figure, where red indicates a radioactive chromatid.
(b) What would the results of Taylor's experiment be if eukaryotes used a conservative mode of DNA replication?
Textbook Question
In the late 1950s, Herbert Taylor grew bean root-tip cells in a solution of radioactive thymidine (a precursor to one of the deoxyribonucleotides in DNA) and allowed them to undergo one round of DNA replication. He then transferred the cells to a solution without radioactive thymidine, allowed them to replicate again, and examined their chromosomes for the presence of radioactivity. His results are shown in the following figure, where red indicates a radioactive chromatid.
(a) Draw labeled diagrams of double-stranded DNA molecules that explain the pattern of radioactivity observed in the sister chromatids after the first and second rounds of replication.
Textbook Question
The graph that follows shows the survival of four different E. coli strains after exposure to increasing doses of ultraviolet light. The wild-type strain is normal, but the other strains have a mutation in either a gene called uvrA, a gene called recA, or both.
(a) Which strains are most sensitive to UV light? Which strains are least sensitive?
1
views