Table of contents

1. Introduction to Anatomy & Physiology5h 43m
2. Cell Chemistry & Cell Components12h 39m
3. Energy & Cell Processes10h 8m
4. Tissues & Histology10h 3m
5. Integumentary System2h 28m
6. Bones & Skeletal Tissue2h 16m
7. The Skeletal System2h 35m
8. Joints2h 17m
9. Muscle Tissue2h 33m
10. Muscles1h 11m
11. Nervous Tissue and Nervous System1h 35m
12. The Central Nervous System1h 6m
- Introduction to the Central Nervous System
  18m
- The Cerebrum
  48m
13. The Peripheral Nervous System1h 26m
14. The Autonomic Nervous System1h 38m
15. The Special Senses2h 41m
16. The Endocrine System2h 48m
17. The Blood3h 22m
18. The Heart3h 42m
19. The Blood Vessels3h 35m
20. The Lymphatic System3h 16m
21. The Immune System14h 37m
22. The Respiratory System3h 20m
23. The Digestive System3h 5m
24. Metabolism and Nutrition4h 0m
25. The Urinary System2h 39m
26. Fluid and Electrolyte Balance, Acid Base Balance37m
27. The Reproductive System2h 5m
28. Human Development1h 21m
29. Heredity3h 32m

2. Cell Chemistry & Cell Components

Endomembrane System: Protein Secretion

Anatomy & Physiology

2. Cell Chemistry & Cell Components

Endomembrane System: Protein Secretion

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Multiple Choice

A researcher made an interesting observation about a protein made by the rough endoplasmic reticulum and eventually found in a cell's plasma membrane. The protein in the plasma membrane was actually slightly different from the protein made in the ER. The protein was probably altered in the __________.

smooth endoplasmic reticulum

plasma membrane

transport vesicles

rough endoplasmic reticulum

Golgi apparatus

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Verified step by step guidance

Understand the role of the rough endoplasmic reticulum (ER): The rough ER is responsible for the synthesis of proteins, particularly those that are to be secreted from the cell or embedded in the cell membrane.

Recognize the function of the Golgi apparatus: The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell. It is a key site for post-translational modification of proteins.

Consider the process of protein modification: After proteins are synthesized in the rough ER, they are transported to the Golgi apparatus in vesicles. Here, they may undergo various modifications, such as glycosylation, phosphorylation, or cleavage.

Identify the pathway of the protein: The protein synthesized in the rough ER is transported to the Golgi apparatus, where it is modified. These modifications can result in a protein that is slightly different from the original version synthesized in the ER.

Conclude that the Golgi apparatus is the site of alteration: Given the role of the Golgi apparatus in modifying proteins, it is the most likely location where the protein was altered before being incorporated into the plasma membrane.