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Multiple Choice
A researcher made an interesting observation about a protein made by the rough endoplasmic reticulum and eventually found in a cell's plasma membrane. The protein in the plasma membrane was actually slightly different from the protein made in the ER. The protein was probably altered in the __________.
A
smooth endoplasmic reticulum
B
plasma membrane
C
transport vesicles
D
rough endoplasmic reticulum
E
Golgi apparatus
Verified step by step guidance
1
Understand the role of the rough endoplasmic reticulum (ER): The rough ER is responsible for the synthesis of proteins, particularly those that are to be secreted from the cell or embedded in the cell membrane.
Recognize the function of the Golgi apparatus: The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell. It is a key site for post-translational modification of proteins.
Consider the process of protein modification: After proteins are synthesized in the rough ER, they are transported to the Golgi apparatus in vesicles. Here, they may undergo various modifications, such as glycosylation, phosphorylation, or cleavage.
Identify the pathway of the protein: The protein synthesized in the rough ER is transported to the Golgi apparatus, where it is modified. These modifications can result in a protein that is slightly different from the original version synthesized in the ER.
Conclude that the Golgi apparatus is the site of alteration: Given the role of the Golgi apparatus in modifying proteins, it is the most likely location where the protein was altered before being incorporated into the plasma membrane.