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Multiple Choice
Consider the currently accepted fluid mosaic model of the plasma membrane. Where in the plasma membrane would cholesterol most likely be found?
A
On the outside (external) surface of the membrane
B
On the inside (cytoplasmic) surface
C
In the interior and on the inside surface but not on the outside surface
D
On either surface of the membrane but not in the interior of the membrane
E
In the interior of the membrane
Verified step by step guidance
1
Understand the fluid mosaic model: The plasma membrane is composed of a phospholipid bilayer with embedded proteins, carbohydrates, and cholesterol. This model describes the membrane as a dynamic and flexible structure.
Identify the role of cholesterol: Cholesterol is a lipid molecule that plays a crucial role in maintaining membrane fluidity and stability. It is interspersed within the phospholipid bilayer.
Locate cholesterol within the membrane: Cholesterol is found within the interior of the membrane, nestled between the phospholipid tails. This positioning helps modulate the fluidity of the membrane by preventing the fatty acid chains of the phospholipids from packing too closely together.
Differentiate between membrane surfaces: The plasma membrane has an external surface facing the extracellular environment and an internal surface facing the cytoplasm. Cholesterol is not limited to either surface but is embedded within the hydrophobic core of the bilayer.
Conclude the location of cholesterol: Based on the fluid mosaic model, cholesterol is most likely found in the interior of the membrane, contributing to its structural integrity and fluidity.